教育经历:
2010 - 2012 , 联合培养博士生 , 分子细胞发育生物学系,耶鲁大学
2007 - 2012 , 理学博士 , 植物学 , 北京大学
2003 - 2007 , 理学学士 , 生物科学 , 武汉大学
工作经历:
2024 - 至今, 北京大学长聘教授,博雅特聘教授
2014 - 至今, 研究员, 博士生导师, 金沙集团wwW3354CC
2012 - 2014 , 博士后 , 分子细胞发育生物学系,耶鲁大学荣誉奖励:
国家杰出青年科学基金,2023
Rising Stars in Plant Sciences, 2023
国家优秀青年科学基金,2018
国家自然科学基金委创新群体, 骨干成员, 2017-2022
国家重点研发计划专项青年项目,首席科学家,2016-2021
入选中国科技协会首批国家“青年人才托举工程”,2016
Monsanto Fellowship award, 2010
杂志任职:
National Science Review、Frontiers in Plant Science杂志编委。评审任职:
2017-至今 国家重点研发计划专项,通讯评审专家;
2016-至今 中国博士后基金,通讯评审专家;
2015-至今 国家自然科学基金(面上,优青,重点,国际合作),通讯评审专家;
2021年-至今,国家“海外优青”人才项目,通讯评审专家;
2021年-至今,教育部“长江学者奖励计划”人才项目,通讯评审专家;
2020年,国家“青年拔尖”人才项目,答辩评审专家;
2022年,国家自然科学基金(面上、青年、地区)项目,会评专家。
会议发言与组织:
2024国际分子植物科学大会,会议报告,上海,2024.8
2024国际植物钙生物学大会,会议报告,葡萄牙,2024.7
2019国际植物光生物学大会,会议报告,西班牙,2019.6
第十一届国际植物激素乙烯大会,会议报告,希腊,2018.6
2018国际植物光生物学大会,会议报告,日本,2018.1
第十九届国际植物学大学, 会议报告,深圳,2017.7
2016全国植物生物学大会,会议报告,武汉,2016.10
第十七届全国植物基因组大会,会议报告,福州,2016.8
第十届国际植物激素乙烯大会,会议报告,重庆,2015.11
第十二届国际植物生物学前沿大会,会议报告,成都,2015.4书籍编撰:
《植物私生活》,执行主编,商务印书馆;
《植物的身体》,编委,商务印书馆;
《植物与食物》,编委,商务印书馆;
《未来作物品种设计》,编委,科学出版社;
《Thermomorphogenesis-Methods and Protocols》,章节撰写,Humana Press。执教课程:
植物与环境, 本科生,研究生,秋季学期,全校公选课,主持,北京大学
光合作用与物质循环,本科生,研究生,秋季学期,专业限选课,主持,北京大学
生物化学小班讨论课,本科生,秋季学期,专业必修课,主持,北京大学
发育生物学,本科生,春季学期,专业必修课,参与,北京大学
植物光生物学与激素前沿进展,研究生,春季学期,全校公选课,主持,北京大学
PTN项目植物学课程,研究生,春季学期,PTN项目模块课,参与,北京大学 随着中国进入老龄化社会和城镇化发展,农业机械化生产是未来趋势。机械化直播中,由于幼苗出土的整齐性和存活率较低,造成大量种子损失,并严重影响了农作物的精细分布。
实验室致力于研究植物(拟南芥、大豆等)对于陆地土壤环境的适应,重点关注植物种子在土壤中萌发,幼苗向上生长破土,以及出土后见光存活的分子调控机制。主要研究内容有:
1)种子萌发,幼苗形态建成及变绿存活;
2)光照、温度、机械压力等环境因子与植物内源激素互作;
3)细胞钙信号编码与解码分子机制;
4)植物应答土壤机械压力(植物触觉)的受体及信号传导通路。
(#equal contribution, *corresponding author)
25. Zhao Y.#, Shi H.#, Pan Y.#, Lyu M., Yang Z., Kou X., Deng X., Zhong S.*, Sensory circuitry controls cytosolic calcium-mediated phytochrome B phototransduction, Cell, 2023, 186: 1230-1243.(该论文由国际著名植物学家Enamul Huq教授在Science Bulletin上、Ferenc Nagy教授在New Phytologist上撰写评述文章推荐,同时被Alex Costa教授、林辰涛教授等在F1000上推荐)
24. Shi H.*, Zhong S.*, Light and temperature perceptions go through a phase separation, Current Opinion in Plant Biology, 2023, 74: 102397. (Invited review)
23. Hwang Y., Han S., Yoo C., Hong L., You C., Le B., Shi H., Zhong S., Hoecker U., Chen X., Chen M.*, Anterograde signaling controls plastid transcription via sigma factors separately from nuclear photosynthesis genes, Nature Communications, 2022, 13: 7440.
22. Chen D., Lyu M., Kou X., Li J., Yang Z., Gao L., Li Y., Fan L., Shi H., Zhong S.*, Integration of light and temperature sensing by liquid-liquid phase separation of phytochrome B, Molecular Cell, 2022, 82: 3015-3029. (Cover story)
(该论文被选为当期封面文章,由国际著名植物学家Enamul Huq教授在同期Molecular Cell上撰写评述文章推荐,同时被Nature structure & Molecular Biology杂志副主编Sara Osman撰写评述做亮点推荐,并被Andrey Kovalevsky教授、杨淑华教授等在F1000上推荐)
21. Wu Q., Zhong S., Shi H.*., MicroProteins: Dynamic and accurate regulation of protein activity, JIPB, 2022, 64: 812-820.
20. Li W., Li Q., Lyu M.., Wang Z., Song Z., Zhong S., Gu H., Dong J., Dresselhaus T., Zhong S., Qu L.*, Lack of ethylene does not affect reproductive success and synergid cell death in Arabidopsis, Molecular Plant, 2022, 15: 354-362.
19. Jiang A., Guo Z., Pan J., Yang Y., Zhuang Y., Zuo D., Hao C., Gao Z., Xin P., Chu J., Zhong S., Li L.*, The PIF1-miR408-PLANTACYANIN repression cascade regulates light-dependent seed germination, Plant Cell, 2021, 33: 1506-1529.
18. Wu Q., Li Y., Lyu M., Luo Y., Shi H., Zhong S.*, Touch-induced seedling morphological changes are determined by ethylene-regulated pectin degradation, Science Advances, 2020, 6 (48), eabc9294.
17. Wu Q., Kuang K., Lyu M., Zhao Y., Li Y., L J., Pan Y., Shi H., Zhong S.*, Allosteric deactivation of PIFs and EIN3 by microProteins in light control of plant development, PNAS, 2020, 117: 18858-18868. (该论文被F1000推荐)
16. Yang C.#, Shen W.#, Yang L.#, Sun Y., Li X., Lai M., Wei J., Wang C., Xu Y., Li F., Liang S., Yang C., Zhong S., Luo M.*, Gao C.*, HY5-HDA9 Module Transcriptionally Regulates Plant Autophagy in Response to Light-to-Dark Conversion and Nitrogen Starvation, Molecular Plant, 2020, 13: 515-531.
15. Lyu M.#, Shi H.#, Li Y., Kuang K., Yang Z., Li J., Chen D., Li Y., Kou X., Zhong S.*, Oligomerization and photo-deoligomerization of HOOKLESS1 controls plant differential cell growth, Developmental Cell, 2019, 51: 78-88.
14. Shi H.#, Lyu M.#, Luo Y.#, Liu S.#, Li Y., He H., Wei N., Deng X.W.*, Zhong S.*, Genome-wide regulation of light-controlled seedling morphogenesis by three families of transcription factors, PNAS, 2018,115: 6482-6487.
13. Liu X., Liu R., Li Y., Shen X., Zhong S.*, Shi H.*, EIN3 and PIF3 Form an Interdependent Module that Represses Chloroplast Development in Buried Seedling, Plant Cell, 2017,29: 3051-3067.
(该论文为Plant Cell发表当月最受关注的top5文章之一,被选为亮点文章,并发表评述文章做重点推荐,同时被F1000推荐)
12. Liu X., Li Y., Zhong S.*, Interplay between Light and Plant Hormones in the Control of Arabidopsis Seedling Chlorophyll Biosynthesis, Frontiers in Plant Science, 2017, 8: 1433.
11. Shi H.#, Shen X.#, Liu R., Xue C., Wei N., Deng X.W.*, Zhong S.*, The red light receptor phytochrome B directly enhances substrate-E3 ligase interactions to attenuate ethylene responses, Developmental Cell , 2016,39:597-610. (cover story)
(该论文被选为当期封面文章,并由国际著名植物学家Jose M. Alonso教授在同期Developmental Cell上撰写评述文章推荐,同时被Science Signaling的Editors` Choice栏目选中发表评述做亮点推荐)
10. Shen X., Li Y., Pan Y., Zhong S.*, Activation of HLS1 by Mechanical Stress via Ethylene-Stabilized EIN3 Is Crucial for Seedling Soil Emergence, Frontiers in Plant Science , 2016 , 7: 1571.
9. Shi H., Liu R., Xue C., Shen X., Wei N., Deng X.W.* , Zhong S.*, Seedlings Transduce the Depth and Mechanical Pressure of Covering Soil Using COP1 and Ethylene to Regulate EBF1/EBF2 for Soil Emergence , Current Biology , 2016 , 26: 139-149.
(该论文由美国科学学院院士Winslow R. Briggs在Current Biology上撰写评述文章推荐,同时被Nature Plants news and views发表评述文章推荐,并被Trends in Plant Science亮点推荐)
8. Shi H., Wang X., Mo X., Tang C., Zhong S.*, Deng X.W.*, Arabidopsis DET1 degrades HFR1 but stabilizes PIF1 to precisely regulate seed germination , PNAS , 2015 , 112 (12): 3817-3822.
7. Zhong S., Shi H., Xue C., Wei N., Guo H., Deng X.W.*, Ethylene-orchestrated circuitry coordinates a seedling`s response to soil cover and etiolated growth , PNAS , 2014 , 111 (11): 3913-20.
(该论文被F1000推荐)
6. Seo K.#, Lee J.#, Nezames C.D.#, Zhong S., Song E., Byun M., Deng X.D.*, ABD1 is an Arabidopsis DCAF Substrate Receptor for CUL4-DDB1-Based E3 Ligases that Acts as a Negative Regulator of Abscisic Acid Signaling , Plant Cell , 2014 , 26: 695–711.
5. Shi H.#, Zhong S.#, Mo X.#, Liu N., Nezames C.D., Deng X.W.*, HFR1 sequesters PIF1 to govern the transcrIptional network underlying light-initiated seed germination in Arabidopsis , Plant Cell , 2013 , 25: 3770–3784.
4. Shen H., He H., Li J., Chen W., Wang X., Guo L., Peng Z., He G., Zhong S., Qi Y., Terzaghi W., Deng X.W.*, Genome-Wide Analysis of DNA Methylation and Gene Expression Changes in Two Arabidopsis Ecotypes and Their Reciprocal Hybrids , Plant Cell , 2012 , 24: 875 -92.
3. Zhong S., Shi H., Xue C., Wang L., Xi Y., Li J., Quail P.H., Deng X.W.*, Guo H.*, A molecular framework of light-controlled phytohormone action in Arabidopsis , Current Biology , 2012 , 22: 1530–1535.
(该论文被Current Biology配以评述文章推荐,并同时被F1000推荐)
2. Zhong S., Shi H., Xi Y., Guo H.*, Ethylene is crucial for seedlings’ chlorophyll synthesis and survival during de-etiolation , Plant Signal & behavior , 2010 , 5: 739–742.
1. Zhong S., Zhao M., Shi T., Shi H., An F., Zhao Q., Guo H.*, EIN3/EIL1 cooperate with PIF1 to prevent photo-oxidation and promote greening of Arabidopsis seedlings , PNAS , 2009 , 106 (50): 21431-21436.